Systematic Calculation of HyperOxygenation Transit Time (SCHOTT)

University Hospital, Angers

Status: Terminated

Conditions: Cardiac Output

Treatments: Diagnostic Test: Transcutaneous oxymetry measurement

Study type: Interventional

Funder types: Other

Identifiers

NCT04007146

2019-002571-33

Details and patient eligibility

About

Cardiac output (CO) is an essential physiological parameter of healthy person or illness.

In clinical practices, all methods of measuring the CO(Fick method, thoracic impedance, esophageal echodoppler etc) contain limit. Each method are dangerous or hard to implement.

CO is probably determining element of blood transit time and thus the availability of oxygen between the central organs (heart, lung) and the peripheral organs (leg, arms).

Our hypothesis is transcutaneous oxymetry mesurement with oxygen inhalation, to cause a transient hyperoxia, can be used to determinate blood transit time between central organs and peripheral organs. This simple method will be non invasive technique.

Full description

At admission eligible patients are proposed to participate. Written consent is signed after complete oral and written explanation of the protocol is signed.

The time of onset hyperoxia will be compare to usual CO method by cross correlation.

The duration of participation for subject is equal to 1 hour.

Enrollment: 1 patient

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults over 18
• Cardiac output measurement considered at least 2 hours prior to the study
• Affiliation to a French National healthcare system
• Written informed consent must be obtained prior to protocol-specific

Exclusion criteria

• Acute or decompensated cardiac or respiratory failure
• Allergy to medical adhesives
• Patients under reinforced protection, pregnancy, deprived of liberty by judicial or administrative decision, hospitalized without consent or admitted to a health or social establishment for purposes other than research
• Inability to understand the instructions or objectives of the study

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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1 participants in 1 patient group

Cardiac Output Measurement

Experimental group

Description:

Subject will have a usual cardiac output

Treatment:

Diagnostic Test: Transcutaneous oxymetry measurement