Systematic IPP VS Symptomatic IPP in GERD Prevention After POEM for Achalasia. . A Comparative Retrospective Analysis (IPPOEM-Retro)

University Hospital Center (CHU)

Status: Unknown

Conditions: Achalasia; Gastroesophageal Reflux

Study type: Observational

Funder types: Other

Identifiers

NCT04740437

RECHMPL21_0064

Details and patient eligibility

About

POEM is a minimally invasive endoscopic therapy that is highly efficacy in the treatment of achalasia of any type. POEM has an increased risk of GERD. Systematic PPI therapy has never been studied for the prevention of post-POEM GERD.

The investigators wish to retrospectively compare patients who have received routine PPI therapy vs. patients who don't.

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• > 18 years old
• Consent given
• Achalasia all types with eckhardt score > 3

Exclusion criteria

• Patient who is a minor or under judicial protection
• Pregnant or breastfeeding woman
• Contraindication to PPIs
• Carrier of mediastinal and exogastric neoplasia
• Patient on PPIs prior to the procedure for indication that does not allow for their discontinuation
• Peptic esophagitis (Grade B, C or D) before or at the time of the procedure
• Previous treatment with Heller myotomy