Systematic Review and Meta-analysis of Cereal or Grain Consumption and Gastric Cancer (GC)

Sichuan University

Status: Completed

Conditions: Gastric Cancer

Treatments: Dietary Supplement: cereal or grain consumption

Study type: Observational

Funder types: Other

Identifier

NCT03419663

Details and patient eligibility

About

This project involved a systematic literature review of published trials of cereal or grain in relation to the risk of gastric cancer. Data was extracted from the publications on PubMed, EMBASE, Cochrane Library.A traditional meta-analysis, subgroup analysis, and heterogeneity was conducted on the extracted data.

Full description

Investigators searched PubMed, EMBASE, Cochrane Library for studies focusing on cereal or grain in relation to the risk of gastric cancer up to October 2017. Summary odd ratios (OR) and 95% confidence intervals (CI) were calculated by using either random effect models or fixed effect models according to the heterogeneity of included studies. Subgroup analysis, heterogeneity, and publication bias were also performed.

Enrollment: 11 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• a case-control studies or a cohort study
• investigate the association between cereal or grain intake and GC occurrence
• report an odds ratio (OR) or relative risk (RR) with corresponding 95% confidence intervals (CI)
• provide sufficient data to estimate OR or RR

Exclusion criteria

• Non-human studies
• GC mortality-based cohort studies

Trial design

11 participants in 1 patient group

gastric cancer

Treatment:

Dietary Supplement: cereal or grain consumption