Systemic Inflammatory Indices as a Non-invasive Grading Modality for Endometriosis

Benha University

Status: Completed

Conditions: Endometriosis

Treatments: Procedure: Diagnostic laparoscopy; Diagnostic Test: Full Blood Count (FBC)

Study type: Observational

Funder types: Other

Identifiers

NCT06298617

RC 27.1.2024

Details and patient eligibility

About

Endometriosis (EMs) is one of the commonest chronic inflammatory disorder affecting women and is characterized by the presence and growth of endometrial-like glandular epithelial and stromal cells outside the uterus leading to multiple clinical symptoms affecting patients quality of life and fertility with high recurrence rate . The systemic immune inflammatory index (SII) and systemic inflammatory response index (SIRI) are documented as prognostic serum biomarker in many kinds of cancer and for the need and outcomes of adjuvant therapies for various cancers .

Enrollment: 88 patients

Sex: Female

Ages: 25 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women with clinical manifestations suggestive of having EM;
• Women who was professionally diagnosed;
• Women who was diagnosed by radiologic workup;
• Women were free of exclusion criteria.

Exclusion criteria

• Women with EM and were maintained on treatment or underwent operative interference during the last three months;
• Patients had autoimmune diseases, maintained on immunosuppressive therapy for any indication;
• Women with cancer elsewhere in the body or receiving adjuvant therapies for cancer;
• Patients receiving therapies for viral disorders especially COVID;
• Patients refusing to undergo the exploratory laparoscopy.

Trial design

88 participants in 1 patient group

Study group

Treatment:

Diagnostic Test: Full Blood Count (FBC)

Procedure: Diagnostic laparoscopy