T-cell-immunity During Standard Radiotherapy in Localised Prostate Cancer

University Hospital Tuebingen

Status: Completed

Conditions: Prostate Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT01376674

UKT_RO_01

Details and patient eligibility

About

Immunological effects of radiotherapy have been described before, but not evaluated in a time-dependant manner.

In order to identify a possible time frame for combination therapies, white blood cells are isolated of samples taken at different time points before during and after standard radiotherapy in patients with localised prostate cancer. The overall activity of the T-cell-system as well as tumor-specific T-cell-response are evaluated.

Enrollment: 22 patients

Sex: Male

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Localised prostate cancer (node negative)
• definitive radiotherapy
• informed consent

Exclusion criteria

• medication including steroids or immunosuppressants