T Wave Alternans in Hemodialysis

Indiana University School of Medicine

Status: Completed

Conditions: Coronary Heart Disease; End Stage Renal Disease; Congestive Heart Failure

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT00296543

0508-02

Details and patient eligibility

About

The purpose of this study is to determine if the hemodialysis procedure changes the risk for cardiac arrest in patients.

Full description

One-third to one-quarter of hemodialysis patients die of sudden cardiac death (SCD). The hemodialysis procedure may theoretically increase the risk of SCD. This study uses T wave alternans, a noninvasive marker of SCD, to objectively determine whether the hemodialysis procedure alters the risk of SCD in hemodialysis patients.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years of age or older
• Normal sinus rhythm

Exclusion criteria

• Inability to give written informed consent
• Active cardiac ischemia
• Pacemaker
• Inability to perform a brief walking treadmill test