T2* MRI Analysis for Sarcoma

Bryan Allen

Status: Completed

Conditions: Sarcoma; Radiotherapy; Magnetic Resonance Imaging

Treatments: Diagnostic Test: T2* Imaging

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT03658343

5P30CA086862 (U.S. NIH Grant/Contract)

201807711

Details and patient eligibility

About

T2* imaging is a method to identify labile iron pools in tumor cells. These iron pools may be linked to better treatment outcomes for specific types of therapy. This is a small pilot study to see if radiation therapy changes the amount of iron in a sarcoma tumor.

Enrollment: 8 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• pathologically confirmed Sarcoma, by biopsy or excision
• prescribed radiation therapy as per standard of care
• treatment to begin within 5 weeks after surgery or biopsy
• ECOG 0, 1, or 2
• ability and willingness to provide informed consent

Exclusion criteria

• < 18 years of age

Trial design

8 participants in 1 patient group

T2* Imaging

Description:

Participants undergo T2\* MRI imaging before beginning their course of radiation therapy and then after completing radiation therapy, about 2 weeks before their surgery.

Treatment:

Diagnostic Test: T2* Imaging