T2 Weighted Imaging of the Liver With Fast Spin Echo MRI

Ottawa Hospital Research Institute

Status: Terminated

Conditions: Liver Disease

Treatments: Device: MRI examinations

Study type: Interventional

Funder types: Other

Identifiers

NCT02186054

T2 Weighted MRI Liver

Details and patient eligibility

About

The purpose of this study is to test two new MRI (magnetic resonance imaging) sequences to see how they compare to previously used imaging sequences as they may improve the quality of abdominal MRI.

Full description

• Approximately 50 patients undergoing routine liver MRI in our practice imaged with one of our 4 clinical scanners will undergo our standard liver MRI protocol with the addition of 2 breath-hold sequences (FSE Flex and eSSFSE) only increasing the scan time by approximately 3 minutes.
• Data will be retrieved from examinations that have been performed from the patient's electronic imaging file stored in our picture archiving and communication system (PACS).
• Images will be completely anonymized. No patient identifiers will be available on the images during the analysis.
• Analyses will include the visual assessment of image quality, presence and severity of imaging artifact and other non-invasive imaging outcomes performed by radiologists blinded to patient information and the type of sequence performed. Data will be presented in a Likert type scale (1=poor, 2=suboptimal, 3=average, 4=above average and 5=excellent) and imaging parameters will be compared using the Wilcoxon sign rank test.

Enrollment: 50 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing routine liver MRI imaged with one of our 4 clinical scanners (MR 750W, General Electric, Milwaukee WI)

Exclusion criteria

• Patients not undergoing routine liver MRI

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind

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50 participants in 1 patient group

Imaging- MRI examinations

Other group

Description:

Liver MRI imaging will be performed on 50 patients.

Treatment:

Device: MRI examinations