Tailored Intervention to Improve Medication Adherence in Patients With Hypertension

Odense University Hospital

Status: Completed

Conditions: Hypertension

Treatments: Behavioral: Complex tailored intervention; Behavioral: Usual care

Study type: Interventional

Funder types: Other

Identifiers

NCT01742923

AKF-384

Details and patient eligibility

About

Patients with hypertension have an increased risk of stroke and myocardial infarction. However, poor adherence to treatment with antihypertensives and lipid-lowering agents occurs frequently within this patient group. The purpose of this study is to investigate whether a complex tailored intervention in a hospital setting will lead to increased medication adherence and fewer cardiovascular events when compared to a usual care group. Interventions focus on motivational interviewing, medication review and telephone follow up.

Enrollment: 532 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Age: 18 years or older

• Patients receiving ambulatory treatment for hypertension in a hospital setting
• The patient or a carer usually dispenses the patient's medications
• Patient lives in the Southern Region of Denmark
• Written consent

Exclusion criteria

• Lives in a care home or institution
• Receive dose dispensed medicine from a pharmacy
• Medicine is dispensed by a nurse in the patient's home
• Correctional mental health patients

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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532 participants in 2 patient groups, including a placebo group

Usual care

Placebo Comparator group

Description:

Usual care

Treatment:

Behavioral: Usual care

Complex tailored intervention

Experimental group

Description:

The interventions consists of 3 elements: 1. Medication review with recommendations focused on antihypertensives and statins and adherence to guidelines and patient´s adherence to medications 2. Consultation with a pharmacist using motivational interviewing techniques 3. Follow-up telephone calls one month and six months after inclusion

Treatment:

Behavioral: Complex tailored intervention