Tailored Intervention to Improve Patient Adherence to Secondary Stroke Prevention Medication

Odense University Hospital

Status: Completed

Conditions: Stroke; Transient Ischemic Attack

Treatments: Behavioral: Complex tailored intervention; Behavioral: Usual care

Study type: Interventional

Funder types: Other

Identifiers

NCT01684176

AKF-381

Details and patient eligibility

About

Patient suffering a Transient Ischemic Attack (TIA) or stroke are subsequently at high risk of a new stroke, however, poor adherence to secondary prevention medications occurs frequently within this patient group. The purpose of this study is to evaluate whether a complex tailored pharmacist intervention will lead to increased adherence to secondary stroke prevention medications and less new stroke events when compared to a usual care group. Interventions focus on motivational interviewing, medication review and telephone follow up.

Enrollment: 211 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age: 18 years or older
• Patient admitted or receiving ambulatory treatment for an acute transient ischemic attack or ischemic stroke which has occurred within the previous 30 days.
• The patient or a carer usually dispenses the patient's medications
• Written consent

Exclusion criteria

• Cognitive or physical impairment that would preclude comprehension of a conversation
• Terminal illness
• Lives in a care home or an institution
• Receives dose dispensed medicine from a pharmacy
• Medicine is dispensed by a nurse in the patient's home
• Correctional mental health patients

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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211 participants in 2 patient groups, including a placebo group

Complex tailored intervention

Experimental group

Description:

The intervention consists of 3 elements: 1. Medication review with recommendations focused on antithrombotics and adherence to guidelines and patient´s adherence to medications. 2. Discharge consultation with an pharmacist using motivational interviewing techniques. 3. Follow-up telephone calls one week, two months and six months after discharge.

Treatment:

Behavioral: Complex tailored intervention

Behavioral: Usual care

Usual care

Placebo Comparator group

Description:

Usual care

Treatment:

Behavioral: Usual care