TAILORx Tissue Bank

Cancer Trials Ireland

Status: Active, not recruiting

Conditions: Breast Cancer

Study type: Observational

Funder types: NETWORK

Identifiers

NCT02050750

ICORG 12-30

Details and patient eligibility

About

This is an exploratory, translational, non-interventional and multi-centre biobank. The aim of the development of such a biobank is to identify potential biomarkers that are indicative of disease relapse.

Full description

The primary objective is to develop a biobank, tissue microarrays (TMAs) and full face sections, which will be used to identify candidate/ novel biomarkers prognostic for disease relapse and predictive for endocrine and/or chemotherapy resistance.

The secondary objectives are:

• To validate emerging signatures/biomarkers identified.
• To develop new assays for the breast cancer clinic.

Enrollment: 600 patients

Sex: Female

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Patients that were registered with the ICORG 06-31 TAILORx trial and participated in trial arms
• Patients with adequate tumor tissue available

Trial design

600 participants in 1 patient group

TAILORx ICORG 06-31

Description:

Patients must have participated in TAILORx ICORG 06-31, participated in trial arms, and have adequate tumour tissue available