Taking Action Together- A Diabetes Prevention Program (TAT)

University of California (UC), Berkeley

Status: Completed

Conditions: Type 2 Diabetes

Treatments: Behavioral: Low Intensity; Behavioral: High Intensity

Study type: Interventional

Funder types: Other

Identifiers

NCT01039116

USDA 2004-35215-14250

Details and patient eligibility

About

The purpose of this study was to determine whether once-weekly exposure to a program that fostered self-esteem building, and improvements in nutrition and physical activity behaviors would reduce risk of type 2 diabetes in overweight, inner-city, African American children when compared to a control group.

Full description

In the United States and, indeed, worldwide the prevalence of overweight and obesity has increased at an unprecedented rate. Concomitant with this demographic change are increases in diseases including type 2 diabetes, cardiovascular disease and some cancers that are associated with body fatness. Strategies to reduce body weight have been largely unsuccessful, making it unlikely that our population will be made healthy simply by recommending that overweight people reduce their body fatness. There is evidence, however, that the impact of body fat on human health can be significantly attenuated by potentially achievable strategies. Such strategies require adequate intakes of essential nutrients, regular physical activity and strong self-esteem. The goal of the project is to reduce the risk of type 2 diabetes mellitus (T2DM) in overweight 9- to 10-year-old African American children through a multi-component community-based program. The specific objectives are to (1).Implement a randomly controlled 2-phase intervention involving a 2-week summer camp, and weekly & monthly reinforcement sessions over 2 years, that include nutrition education, physical activity promotion, and self-esteem and self-efficacy building and (2) Test effectiveness of the program after 1 and 2 years of intervention on insulin sensitivity, the primary outcome, and on secondary outcomes including body fatness, dietary intakes, physical activity, and self-esteem. Identifying an effective, community-based program that could reduce risk of type 2 diabetes in high-risk children would promote health, reduce disease and reduce health-care costs in the future.

Enrollment: 240 patients

Sex: All

Ages: 9 to 11 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Child age of 9-10 yr old at baseline
• Child BMI at least 85th percentile when matched for age and gender
• Able and willing to participate in normal daily activities
• Living in inner-city regions of Oakland CA

Exclusion criteria

• Fasting blood glucose of 120 mg/dl or higher
• Diagnosis of diabetes or other central metabolic disease
• Taking medications that interfere with or treat main study outcomes

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

240 participants in 1 patient group

Level of intervention intensity

Experimental group

Description:

High Intensity: Behavioral Experimental:Participating children were invited to attend a 2 week summer day camp at the beginning of each intervention year, and to attend a weekly, 2 hr interactive session for children. Activities provided hand-on experiences preparing and tasting healthy food alternatives, engaging in a range of physical activities and self-esteem boosting via activities that promoted communication and positive behavioral development. Active Comparator: Low-intensity Participants were provided with educational materials 4 times yearly.

Treatment:

Behavioral: Low Intensity

Behavioral: High Intensity