Taking Measurements of a Gum Graft Site as it Heals

The Ohio State University

Status: Not yet enrolling

Conditions: Gingival Recession

Treatments: Procedure: Gingival graft surgery to treat gingival recession

Study type: Observational

Funder types: Other

Identifiers

NCT07386457

2025H0007

Details and patient eligibility

About

This is an observational study. The participants in this study will be patients at the Graduate Periodontics Clinic at The Ohio State University who are planning to get a gingival graft to treat their gum recession. Gingival grafts are a common way to treat this recession. The grafting surgery is not part of the study.

The main purpose of this study is to better understand the normal healing of a gum graft. In order to do that, the investigators will take different kinds of measurements.

1. It is common for the tissue around the graft to have some swelling after the surgery. The investigators will measure the amount of swelling at different times as the graft heals. This will be done with a digital scanner which is passed over the area.
2. They will use a device which measures blood flow, so they can see how new blood vessels are forming. This is also a device which is only passed over the area, so it is not invasive.
3. They will take saliva samples from around the teeth using sterile paper strips. This fluid will be analyzed for substances related to wound healing.
4. They will ask the participants to fill out questionnaires about their experience with the graft healing.

Enrollment: 15 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical (oral) Ohio State University College of Dentistry patient, treatment planned for SCTG procedure
• Miller Recession Class I, II, or III
• Teeth; Maxillary or mandibular incisors, canines, pre-molars
• Gingival Index ≤ 1
• Plaque Index ≤ 1
• Able and willing to provide informed consent
• Able and willing to complete questionnaire

Exclusion criteria

• Carious lesions on the tooth selected for surgical root coverage
• Taking any medications affecting the gingiva and/or oral mucosa: phenytoin, calcium channel blockers , cyclosporin A, immunostimulants/ immunomodulators
• Quantitative and/or qualitative PMN defects
• Organ transplant(s)
• Type I or II diabetes
• Currently pregnant or lactating
• Usage of smokeless tobacco
• Physical/mental handicap which can interfere with adequate oral hygiene performance

Trial design

15 participants in 1 patient group

Grafting Surgery Recipients

Description:

Patients at the Graduate Periodontics Clinic at The Ohio State University who are having a gingival graft done to treat gingival recesssion.

Treatment:

Procedure: Gingival graft surgery to treat gingival recession