Tamoxifen Pharmacogenetics in Asian Breast Cancer Women

Inje University

Status: Unknown

Conditions: Poisoning by, Adverse Effect of and Underdosing of Tamoxifen

Study type: Observational

Funder types: Other

Identifiers

NCT01181518

09-140

Details and patient eligibility

About

The clinical outcome of tamoxifen treatment in breast cancer patients may be influenced by the activity of cytochrome P450 enzymes involving in tamoxifen biotransformation.

Full description

The investigators investigated the prognostic and/or predictive value of genetic polymorphisms of enzymes involved in tamoxifen metabolism for the treatment outcome among Asian breast cancer patients.

Enrollment: 1,000 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• incident breast cancer patients who underwent surgery

Exclusion criteria

• previous cancer history before breast cancer diagnosis