TAP Block With Two Different Doses of Levobupivacaine

Ankara University

Status and phase: Unknown; Phase 4

Conditions: Pain, Postoperative

Treatments: Drug: Levobupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT02567487

931893045140401

Details and patient eligibility

About

The aim of the current study is to investigate the effects of two different doses of levobupivacaine in TAP (transversus abdominus plane) block for postoperative management. For this purpose we planned to include 50 children aged between 2 and 12 that will undergo unilateral inguinal surgery.

The doses that will be used in the study were within usual dose limits which is stated in prospectus of the study drug.

Full description

Fifty children undergoing TAP block were randomly divided into two groups as levobupivacaine 0.25% 0.5 ml/kg and levobupivacaine 0.25% 0.25 ml/kg. Postoperative pain was evaluated with observational pain scale and modified pediatric objective pain scale.

Enrollment: 50 estimated patients

Sex: All

Ages: 2 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Volunteers planned to undergo unilateral inguinal surgery under TAP (ilioinguinal and iliohypogastric block) and general anesthesia
• Aged between 2 and 12

Exclusion criteria

• Patients with coagulation dysfunction
• Patients with chronic pain
• Patients having infection at the site of intervention
• Patients with a history of allergy
• Patients having chronic diseases (hepatic dysfunction, renal failure)

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

50 participants in 2 patient groups

Group Levobupivacaine high volume

Active Comparator group

Description:

TAP block with levobupivacaine 0.25% of 0.5 ml/kg under general anesthesia

Treatment:

Drug: Levobupivacaine

Group Levobupivacaine low volume

Active Comparator group

Description:

TAP block with levobupivacaine 0.25% of 0.25 ml/kg under general anesthesia

Treatment:

Drug: Levobupivacaine