TAP vs. ESP Block for Gynecological Post Operative Pain

Universitas Padjadjaran

Status: Completed

Conditions: Nerve Block; Pain, Postoperative

Treatments: Procedure: Erector Spinae Plane Block using 0.25% Bupivacaine; Procedure: Transversus Abdominis Plane Block using 0.25% Bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT06044779

AN-202309.03

Details and patient eligibility

About

The goal of this double blind randomized controlled trial is to compare transversus abdominis plane block and erector spinae plane block in gynecological surgery patients. The main questions it aims to answer are:

• What are the numerical post-operative pain scores in these two groups?
• Is there any significant difference in the numerical post-operative pain scores between subjects who underwent TAP block and subjects who underwent ESP block?
• What are the differences in the time needed for additional morphine in these two groups?
• Is there any significant differences in the time needed for additional morphine between subjects who underwent TAP block and subjects who underwent ESP block?

Enrollment: 40 patients

Sex: Female

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects with gynecological surgery techniques with a median incision include: hysterectomy, myomectomy, salpingectomy, ovarectomy and ovarian cystectomy.
• Subjects with physical status based on the American Society of Anesthesiologists (ASA) in categories I-II
• Subjects who are willing to sign informed consent form.

Exclusion criteria

• The patient has a history of allergies to local anesthetic drugs used for TAP blockade or ESP blockade and is allergic to morphine.
• Patients who have skin infections at the injection site.
• Patients with a history of chronic pain, namely a history of pain for more than 1 month obtained from history taking.
• Patients with a history of chronic pain treatment obtained from history taking.
• Patients with impaired kidney function (Ureum >39 mg/dL; Creatinine >1.3 mg/dL) and liver (SGOT >37 U/L; SGPT >59 U/L), myopathy, coagulopathy obtained from the results of supporting examinations, heart rhythm disorders obtained from the results of an EKG examination and neurological disorders in the form of hypesthesia or paraesthesia obtained from the results of a physical examination in the form of a sensory examination.
• The patient is pregnant as determined by history taking.
• Patients who are illiterate as obtained from history taking.
• The patient was uncooperative during examination.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups

Transversus Abdominis Plane (TAP) Anesthestic Block

Active Comparator group

Description:

Ultrasound-guided TAP block is done using 20 mL of 0.25% Bupivacaine administered at the lateral abdominal wall between the costal margin and the iliac crest

Treatment:

Procedure: Transversus Abdominis Plane Block using 0.25% Bupivacaine

Erector Spinae Plane (ESP) Anesthetic Block

Active Comparator group

Description:

Ultrasound-guided ESP block is done using 20 mL of 0.25% Bupivacaine administered at the tip of the transverse process at the T9 level

Treatment:

Procedure: Erector Spinae Plane Block using 0.25% Bupivacaine