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Targeting Taboo Thoughts In Obsessive-Compulsive Disorder

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Karolinska Institute

Status

Completed

Conditions

Obsessive-Compulsive Disorder

Treatments

Other: Online cognitive therapy (I-CT)

Study type

Interventional

Funder types

Other

Identifiers

NCT04313439
EPN Dnr 2019-06047

Details and patient eligibility

About

The purpose of this pilot study is to investigate if a cognitive treatment targeting obsessive beliefs in patients with aggressive obsessions is feasible and effective as an online treatment.

Full description

Patients with obsessive-compulsive disorder who presents with aggressive obsessions (also known as taboo thoughts e.g. fear of being a pedophile) and mental rituals have shown to respond less well to treatment. Thus, there is room for further innovation. The primary objective of this pilot study is to investigate if an internet-based cognitive therapy (I-CT) is feasible and effective in reducing the frequency and distress of aggressive obsessions. The study will also investigate if I-CT is associated with any significant side effects. Another objective of this study is to get a power estimate of the treatment effects for a subsequent randomized controlled study (RCT). This will be done by using an open pilot study with repeated measurements.

Enrollment

19 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Diagnosis of OCD taboo thoughts as specified in the DSM-5
  • ≥ 18 years
  • Situated in Sweden
  • Informed consent

Exclusion criteria

  • No signed consent
  • Not fluent speaking in Swedish or cognitive abilities to read written material in the study
  • Adjusted pharmacological treatment the last month symptoms that may affect OCD symptoms
  • Substance dependence during the last six months
  • Psychosis
  • Ongoing mania or hypomania
  • Suicidal risk that may affect study participation
  • Personality disorder that may significantly affect the treatment participation
  • Other ongoing psychological treatments that may affect OCD-symptoms
  • Other primary psychiatric diagnosis

Trial design

Primary purpose

Treatment

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

19 participants in 1 patient group

Treatment
Experimental group
Description:
Online Cognitive Therapy (I-CT)
Treatment:
Other: Online cognitive therapy (I-CT)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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