Taste Perception Pre and Post Bariatric Surgery (RBtaste)
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Details and patient eligibility
About
The investigators wish to study the effects of three forms of bariatric surgery, gastric bypass lap banding, and sleeve gastrectomy. The surgery is not part of the clinical trial. If your insurance does not cover the procedure, then the patient is responsible for payment of the surgical process. The investigators are doing pre and post surgery testing to provide a better understanding of the effect of bariatric surgery-induced weight-loss on taste perception.
Full description
Bariatric surgery is the most effective weight loss therapy for obesity. However, the mechanisms responsible for decreased food intake are incompletely understood. One possible mechanism that could account for decreased food intake is changes in taste perception. Therefore, the primary goal of this proposal is to provide a better understanding of the effects of bariatric surgery-induced weight-loss on taste perception.
Enrollment
Sex
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Volunteers
Inclusion criteria
- BMI >=35 kg/m²
- on stable dose of medication for at least 4 weeks before the pre-surgery studies
- women
Exclusion criteria
- smokes > 7 cigarettes per day
- previous malabsorptive or restrictive intestinal surgery
- pregnant or breastfeeding
- recent history of neoplasia (< 5 years ago)
- have malabsorptive syndromes and inflammatory intestinal disease
- diabetes mellitus
- show signs of oral disease or xerostomia (i.e. dry mouth)
- history of chronic rhinitis
- on medication that might affect taste
- severe organ disfunction
Trial design
33 participants in 3 patient groups
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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