Taste Test Between Desloratadine and Cetirizine Syrup in Children (Study P03826)

Organon

Status and phase: Completed; Phase 3

Conditions: Allergic Rhinitis

Treatments: Drug: Desloratadine (Clarinex); Drug: Cetirizine (Zyrtec)

Study type: Interventional

Funder types: Industry

Identifiers

NCT00794794

P03826

Details and patient eligibility

About

This study was conducted to compare the taste acceptability of Zyrtec syrup with desloratadine syrup in children. Children between 6 and 11 years of age received 5 mL of each syrup, separated by 15 to 20 minutes on a single day.

Full description

This study is a cross-over study design.

Enrollment: 204 patients

Sex: All

Ages: 6 to 11 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Subjects must be:

• Between 6 and 11 years of age in good general health
• Premenarcheal if female

Exclusion criteria

Subjects who:

• Have known allergies or sensitivities to either of the drug formulations
• Have a medical condition that may interfere with the subject's ability to discriminate between tastes
• Have used any antihistamines within 24 hours prior to dosing
• Were taking sedatives, tranquilizers, or monoamine oxidase inhibitor drugs
• Were involved in another clinical or market research study within the past 30 days

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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204 participants in 1 patient group

Desloratadine and Cetirizine Crossover

Experimental group

Description:

To compare the preference in taste between desloratadine and cetirizine.

Treatment:

Drug: Cetirizine (Zyrtec)

Drug: Desloratadine (Clarinex)