Taurolock for Preventing Bacterial Peritonitis During Renal Insufficiency

Centre Hospitalier Universitaire de Nīmes

Status

Completed

Conditions

Catheter-related Infections

Peritonitis

Renal Insufficiency

Treatments

Other: Placebo

Device: Taurolock

Study type

Interventional

Funder types

Other

Identifiers

NCT01101087

2009-A00599-48 (Other Identifier)

PHRC-N/2009/BB

Details and patient eligibility

About

Dialysis catheters are sites of bacterial proliferation. The purpose of this study is to determine whether or not the use of Taurolock (a catheter lock solution) can prevent bacterial peritonitis in patients undergoing peritoneal dialysis.

Enrollment

150 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

18 years or older
Renal insufficiency, stage V (HAS 2007 classification)
Requires incident peritoneal dialysis
No signs of peritoneal infection on inclusion
signed consent
affiliated with a social security system

Exclusion criteria

Patient will have a renal transplant in the upcoming year following dialysis
Survival prognosis for one year is weak
allergy to citrate, (cyclo)-taurolidine, or heparin
patient is taking medication with a known contra-indication with citrate or (cyclo)-taurolidine
patient has a thrombopenia caused by heparin
impossible to inform the patient correctly
patient under guardianship
patient already included in another biomedical research protocol
no signed consent
no social security system