Taxane Induced Peripheral Neuropathy in Chinese Patients With Breast Cancer

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Unknown

Conditions: Breast Cancer

Treatments: Other: Patient Questionnaires; Other: Blood Collection

Study type: Observational

Funder types: Other

Identifiers

NCT04068090

TIPN in China

Details and patient eligibility

About

The purpose of this study is to collect clinical data, blood samples, and self reported symptoms of peripheral neuropathy from Chinese patients with breast cancer after treatment with taxanes. This data will be used to develop predictive markers for neuropathy.

Enrollment: 500 estimated patients

Sex: Female

Ages: 16+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Diagnosis of breast cancer
• Females aged 16 and older
• Planning to receive or previous treated with taxanes

Exclusion criteria

• Poorly controlled or insulin-dependent diabetes or other condition likely to predispose to neurotoxicity

Trial design

500 participants in 2 patient groups

Patients with CIPN

Description:

Patients with peripheral neuropathy after treatment with taxanes

Treatment:

Other: Blood Collection

Other: Patient Questionnaires

Patients without CIPN

Description:

Patients treated with taxanes and don't develop will be enrolled to this cohort and matched to a specified subject with neurotoxicity based on age, tumor stage, chemotherapy regimen or total taxane dosage

Treatment:

Other: Blood Collection

Other: Patient Questionnaires