TCA 15% Chemical Peel for Improvement in Hand Lentigines

Main Line Center for Laser Surgery

Status and phase

Enrolling

Phase 4

Conditions

Lentigo

Photoaging

Treatments

Drug: 15% Trichloroacetic acid + 3% glycolic acid

Study type

Interventional

Funder types

Other

Identifiers

NCT05471947

SC20220721

Details and patient eligibility

About

This study will evaluate the efficacy of the a 15% trichloroacetic acid + 3% glycolic acid peel combination for treatment of lentigines on the hands. This peel combination is sold over the counter. Patients will receive 3 treatments (spaced 4 weeks).

Full description

This clinical investigation is a prospective study consisting of a screening visit, 3 treatment visits, and 1 follow-up visit. Baseline and post-treatment photos will be graded and compared.

A total of 20 patients will be recruited. Following informed consent and screening, subjects' dorsal hands will be photographed.

Patients will receive 3 treatments with the 15% TCA + 3% glycolic acid peel every 4-6 weeks on the dorsal hands. Post-treatment, patients will be instructed to apply Aquaphor to the treated area twice daily for 5 days. Patients' hands will be photographed at each visit.

Four to six weeks after their final treatment, subjects will return for photography.

Enrollment

20 estimated patients

Sex

All

Ages

22+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Age >21
No laser, chemical peel, neuromodulator, filler treatment to the hands in >3 months
At least 5 lentigines on each hand

Exclusion criteria

Pregnancy
Breastfeeding
Allergy to trichloroacetic acid
Allergy to glycolic acid
Open wounds on treatment area (hands)
Active inflammatory disease on treatment area such as atopic dermatitis, psoriasis, dermatomyositis