TCF7L2 Polymorphisms Influence on Glycemic Control in ICU Patients With Organ Failure (READIAB-G4)

University Hospital, Lille

Status: Completed

Conditions: Multiple Organ Failure; Hyperglycemia; Genetic Predisposition to Disease; Intensive Care Unit Syndrome

Treatments: Genetic: genetic analysis; Biological: blood and stools samples

Study type: Observational

Funder types: Other

Identifiers

NCT03055169

2010-A00997-32 (Other Identifier)

2009_58

Details and patient eligibility

About

This study evaluates the link between genetic polymorphisms as r7903146, rs12255372 of TCF7L2 gene and the risk of developing hyperglycemia during Intensive care unit stay

Enrollment: 994 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• admission in ICU>48h
• at least one organ dysfunction

Exclusion criteria

• age< 18 years
• pregnant women
• admission less than 48h

Trial design

994 participants in 1 patient group

intensive care patients

Description:

patients with a least one organ dysfunction

Treatment:

Biological: blood and stools samples

Genetic: genetic analysis