TDCS Combined With CT In Opioid Use Disorder (OpiStim)

Istanbul University

Status: Completed

Conditions: Opioid Use Disorder

Treatments: Device: transcranial Direct Current Stimulation; Procedure: Cognitive training

Study type: Interventional

Funder types: Other

Identifiers

NCT05568251

2018-438

Details and patient eligibility

About

The aim of the present study is to investigate the effect of prefrontal transcranial Direct Current Stimulation (tDCS) combined with cognitive training on cognitive functions in individuals with Opioid Use Disorder (OUD). The participants will be allocated into active/sham groups (1:1) and will receive a single session of prefrontal tDCS combined with cognitive training. Outcomes of the active and sham groups will be compared.

Enrollment: 38 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Being aged between 18-65 years
• being in the maintenance phase of the OUD treatment
• naivety to tDCS
• at least 5 years of education

Exclusion criteria

• current diagnosis of major depressive disorder
• current diagnosis or history of bipolar disorders, psychotic disorders, neurocognitive disorders, pervasive developmental disorders, mental retardation, severe neurological disorders,
• common tDCS contraindications

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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38 participants in 2 patient groups

Active tDCS combined with Cognitive Training

Active Comparator group

Treatment:

Procedure: Cognitive training

Device: transcranial Direct Current Stimulation

Sham tDCS combined with Cognitive Training

Sham Comparator group

Treatment:

Procedure: Cognitive training

Device: transcranial Direct Current Stimulation