TDCS in Acute Stroke (TDCS-aphasia)

Charité University Medicine Berlin

Status: Unknown

Conditions: Stroke

Treatments: Device: Sham-TDCS; Device: DKI ED2011

Study type: Interventional

Funder types: Other

Identifiers

NCT01701713

EA4/109/08 (Other Identifier)

TDCS_CSB-Brandenburg

Details and patient eligibility

About

The purpose of this study is to determine the safety of transcranial direct current stimulation in aphasia therapy in acute and post-acute stroke.

Full description

TDCS has been shown to have a positive effect on clinical outcome in both motor rehabilitation and aphasia treatment in chronic aphasic patients. In healthy subjects the method sped up reaction times in naming and language learning tasks. In TDCS a weak current is applied to the subjects head increasing excitatory activity which might lead to improved brain function.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• first media stroke
• language impairment
• informed consent
• right handedness
• NIHSS < 20

Exclusion criteria

• previous Epilepsy oder epileptogenic events
• epilepsy typical elements in EEG
• hypersensitive skin (head)
• metal implants (head)
• pace maker or other electronic implants
• previous head/brain surgery
• medication reducing seizure threshold
• previous psychiatric events

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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100 participants in 2 patient groups

TDCS - DKI ED2011

Experimental group

Description:

TDCS with DKI ED2011 session is followed by a behavioral naming therapy with different cues

Treatment:

Device: DKI ED2011

Sham-TDCS

Sham Comparator group

Description:

Sham-TDCS session is followed by a behavioral naming therapy with different cues

Treatment:

Device: Sham-TDCS