tDCS Response Prediction Using EEG in Stroke

Seoul National University

Status: Unknown

Conditions: Rehabilitation; Motor Recovery; Stroke; Transcranial Direct Current Stimulation

Treatments: Device: Cathodal transcranial direct current stimulation (tDCS) over the contralesional motor cortex

Study type: Observational

Funder types: Other

Identifiers

NCT04830631

B-2004/608-004

Details and patient eligibility

About

Patients with chronic stroke (>6 months after stroke) having unilateral upper limb hemiparesis will be recruited. Patients will maintain their usual inpatient rehabilitation including occupational therapy. At baseline (T0) and after 2weeks of enrollment (T1), Fugl-Meyer assessment (FMA) will be assessed at each time. And patients with the changes of FMA between T0 and T1 less than 3 points will be finally recruited. The enrolled patients will receive additional 30-min cathodal transcranial direct current stimulation (tDCS) over the contralesional motor cortex for 10 consecutive weekdays, with maintaining their usual conventional rehabilitation. At T1 and immediately after 10-seessions of tDCS (T2) and 1 month after completing 10-tDCS session (T3), FMA, Actional Research Arm Test (ARAT), Box and Block Test (BBT) and electroencephalography (EEG) were measured.

Enrollment: 100 estimated patients

Sex: All

Ages: 19 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age ranges from 19 to 85 yrs old
• stroke patients with unilateral hemiparesis
• 1st ever stroke
• chronic stroke (>6 months after stroke)

Exclusion criteria

• recurrent stroke
• history of traumatic brain injury
• Minimental state examination score is 15 or less.
• Unstable medical conditions
• Severe delirium, disorders of consciousness
• pregnancy
• can not attach tDCS electrode on the scalp due to skin conditions
• can not maintain the sitting position
• intracranial metals