Tea Components, Mental Stress and Blood Pressure
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About
Assess the effects of adding theanine to a caffeinated beverage on changes in blood pressure during acute mental stress.
Full description
Caffeine and (mental) stress can increase blood pressure. In a typical everyday and/or work environment they commonly coincide. Tea has the reputation of being a relaxing drink. L-theanine is an amino acid found almost exclusively in tea. In a previous study it was shown that caffeine increased blood pressure, while theanine antagonised these effects. In the current study the effect of theanine to a placebo on blood pressure are directly compared.
Enrollment
Sex
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Volunteers
Inclusion criteria
- Apparently healthy males and females
- Women taking the contraceptive pill
- 18-45 years of age
- BMI 20-30 kg/m2
- Normal or corrected vision
- Low caffeine consumers (<100mg/day)
- Non smokers and having been a non-smoker for > 6 months
- Fluent English
- Normotensive (>90/60 <140/90 mmHg)
Exclusion criteria
- Significant current or medical history of cardiovascular disease
- Low or high STAI trait score in the opinion of the PI
- Known sensitivity to caffeine or theanine
- Colour blindness
- Alcohol consumption above 14/21 units female/male resp. per week
- Weight loss diet > 10% of bodyweight in the previous year
- Anyone with a dependency on PI or staff of Department of Epidemiology and Public Health or being an employee of Unilever
- Reported participation in another biomedical study < 3 months before screening
Trial design
Primary purpose
Allocation
Interventional model
Masking
56 participants in 2 patient groups, including a placebo group
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Data sourced from clinicaltrials.gov
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