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Team Approach to Polypharmacy Reduction to Improve Mobility Long-Term Care

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McMaster University

Status

Terminated

Conditions

Polypharmacy
Medication Therapy Management
Multi-morbidity

Treatments

Other: TAPER

Study type

Observational

Funder types

Other

Identifiers

NCT03202264
TAPER-Mobility

Details and patient eligibility

About

Medication side effects and interactions between medications are very common in older adults and are related to negative health outcomes, including mobility. In this study, the investigators will test a new process aimed at reducing unnecessary medication use and drug side effects in seniors using the best medical evidence and patient preferences for treatment. This study will assess how feasible the implementation of this intervention is within a long-term care facility as well as if it is possible. The study will also assess for any signals of reversal of medications related mobility impairments to reduce medications-related mobility impairment (fatigue, pain, falls) using the intervention. Participants in two long-term care facilities will participate in this study. Measures will include feasibility outcomes regarding the logistics of the intervention as well as patients outcomes (falls, hospitalizations, and medications) collected before and after implementation. Findings will inform the design of a randomized controlled trial to test the effect of this intervention on health outcomes.

Full description

There are substantial associations between polypharmacy and reduced function from older adults and this is likely to be important in frail older adults both in long term care and in the community. The reversibility of drug-induced mobility impairment is unclear therefore the investigators plan to investigate signals of any impact of reducing polypharmacy on mobility. The investigators chose the long-term care setting given the presence of complete medication administration records and this patient population's high prevalence of polypharmacy and risk of adverse drug events. TAPERMD is an electronic tool for systematic medication reduction that incorporates patient priorities, electronic screening for potentially harmful medicines, supporting evidence tools and a monitoring pathway to support medication reduction. This study will examine the feasibility of this tool in a long-term care setting as well as examine. Participants in two long-term care facilities will participate in this study. Measures will include feasibility outcomes regarding the logistics of the intervention as well as patients outcomes (falls, hospitalizations, and medications) collected before and after implementation. Findings will inform a randomized controlled trial to measure the effect of this intervention on health outcomes.

Enrollment

30 patients

Sex

All

Ages

70+ years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

  • residing in 2 long-term care facilities in Brampton, ON
  • on 5 or more medications
  • 70 years of age or older
  • adequate English language

Trial design

30 participants in 1 patient group

TAPERMD
Description:
80 Long term care residents on 5 or more medications aged over 70 from 2 long term care facilities
Treatment:
Other: TAPER

Trial documents
1

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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