TEAS Reduces Remifentanil Consumption (TRIM)

Air Force Military Medical University of People's Liberation Army

Status: Completed

Conditions: Pain; Anesthesia

Treatments: Device: dual acupoints; Device: single acupoint; Device: acupoint stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT03912688

XJA-S-20190212

Details and patient eligibility

About

Transcutaneous electrical acupoint stimulation (TEAS) has been shown to decrease the need of opioids including remifentanil during anaesthesia. However, it is not clear whether combination of two or more acupoints could induce stronger analgesia. Moreover, evidence for the long-term effect of TEAS has been limited. The present study was to compare the short-term and long-term effect on pain of dual-acupoint and single-acupoint TEAS.

Enrollment: 153 patients

Sex: Female

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 to 65 yrs
• body mass index (BMI) of 18 to 30 kg/m2
• elective radical mastectomy under general anaesthesia

Exclusion criteria

• contradictions to TEAS
• difficulties in communication
• histories of general anaesthesia
• drug or alcohol abuse or addiction
• cardiac dysfunction or severe hypertension
• confirmed hepatic dysfunction and renal impairment
• the participants recruited into other clinical trials during last three months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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153 participants in 3 patient groups

single acupoint stimulation

Experimental group

Treatment:

Device: acupoint stimulation

Device: single acupoint

dual acupoints stimulation

Experimental group

Treatment:

Device: acupoint stimulation

Device: dual acupoints

no stimulation

No Intervention group