Telegenetics or In-Person Genetic Counselling

National Cancer Centre, Singapore

Status: Enrolling

Conditions: Genetic Counselling

Treatments: Other: Patients referred to CGS at NCCS for HBOC or Lynch syndrome pre-test genetic counselling.

Study type: Observational

Funder types: Other

Identifiers

NCT04738708

002.1

Details and patient eligibility

About

This study aims to compare clinical outcomes (informed choice and genetic counselling outcomes) and cost (provider and patient time, travel, and telehealth platform) between telegenetics and in-person genetic counselling.

Full description

This study will compare the patient-reported outcomes of telegenetics with in-person consultations for participants considering germline testing for HBOC or Lynch syndrome. It will clarify if telegenetics is a feasible and non-inferior alternative to in-person cancer genetic counselling. Participant responses are important stakeholder views to guide the design of telegenetics to become a mainstream service delivery model welcomed by patients.

It aims to recruit 150 prospective consecutive patients attending genetic counselling for Hereditary Breast and Ovarian Cancer (HBOC) and Lynch Syndrome in Clinical Genetic Services (CGS) at National Cancer Centre Singapore (NCCS).

Upon completion of the genetic consultation appointments, patients will be completing a series of questions evaluating cognitive and psychosocial outcomes either via hardcopy in-person or online internet-facing questionnaire.

Enrollment: 150 estimated patients

Sex: All

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 21 years old.
• Patients referred to CGS at NCCS for HBOC or Lynch syndrome pre-test genetic counselling.
• Able to read and understand the English Language.
• Able to consent and agree to be randomized to either telegenetics or in-person genetic counselling.

Exclusion criteria

• Under the age of 21 years old.
• Patients who require genetic results urgently.
• Cognitive difficulty/ impairment or current psychiatric or physical illness (visual/ hearing/ neurological) which impairs sound judgement and accurate reporting of medical history over video consultation.

Trial design

150 participants in 1 patient group

Patients referred to CGS at NCCS for HBOC or Lynch syndrome pre-test genetic counselling.

Description:

Patients attending genetic counselling for Hereditary Breast and Ovarian Cancer (HBOC) and Lynch Syndrome in Clinical Genetic Services (CGS) at National Cancer Centre Singapore (NCCS)

Treatment:

Other: Patients referred to CGS at NCCS for HBOC or Lynch syndrome pre-test genetic counselling.