TeleRehabilitation in Hypertension (TRiHYP)

Catholic University (KU) of Leuven

Status: Completed

Conditions: Hypertension; Healthy; Pre-hypertension

Treatments: Other: Aerobic endurance training; Other: Isometric handgrip exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT02705911

1502214N

Details and patient eligibility

About

The purpose of this RCT which will be performed in 60 healthy adults is I. To assess the training effects of 8 weeks of isometric handgrip exercise on BP; and to test whether it yields at least similar effects on BP compared to current exercise recommendations.

II. To assess whether isometric handgrip training yields larger BP reductions beyond the supervised training period at 6 months of follow-up.

III. To determine whether changes in BP following acute exercise and chronic training can be explained by changes in important physiological mechanisms known to mediate or to be associated with BP?

Enrollment: 60 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• not physically active (< 3 hours of moderate to high levels of PA/week) low cardiovascular risk according to current guidelines (Mancia et al J Hypertens 2013) will be recruited through advertisements. The latter is defined as:
• >115 mmHg < systolic BP < 139 mmHg and/or 75 mmHg< diastolic BP<90mmHg in the presence of 0 to a maximum of three other cardiovascular risk factors, excluding diabetes Or
• 139 mmHg < systolic BP < 160 mmHg and/or 90 mmHg<DBP< 100 mmHg in the absence of other cardiovascular risk factors

Exclusion criteria

• current smoker
• pregnancy
• presence of other cardiovascular disease, pulmonary disease or metabolic disease
• inability to perform a standard exercise program due to mental/physical disability.
• use of antihypertensive drugs

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 3 patient groups

Isometric Handgrip training

Experimental group

Description:

Participants are asked to perform daily 4 x 2 minute contractions with alternating hands , separated with 1 minute rest period using a ZonaHealth device;

Treatment:

Other: Isometric handgrip exercise

Aerobic endurance training

Active Comparator group

Description:

Participants are asked to perform at least 150 minutes extra of moderate aerobic exercise per week

Treatment:

Other: Aerobic endurance training

Control

No Intervention group

Description:

Participants are asked to continue with their daily routine and not to perform extra exercise.