Temperature Management on Postoperative Delirium (POD)

Wang Hongjian

Status: Not yet enrolling

Conditions: Emergence Delirium

Treatments: Device: 3M™ Bair Hugger™ Warming Unit

Study type: Interventional

Funder types: Other

Identifiers

NCT06406257

2024-keyan-045

Details and patient eligibility

About

Presently, the effects of perioperative temperature management on postoperative delirium remain ambiguous. This study endeavors to explore the influence of intraoperative temperature variations in elderly hip fracture patients on postoperative delirium.

Full description

At present, the pathophysiological mechanisms contributing to postoperative delirium in elderly hip fracture patients remain elusive, with predominant research concentrating on neural inflammation, neurotransmitter dysregulation, and metabolic irregularities. The influence of perioperative temperature management on postoperative delirium remains uncertain and may correlate with surgical modality and intraoperative temperature modulation. Hence, this study endeavors to juxtapose intraoperative temperature variations among elderly hip fracture patients, probing their ramifications on postoperative delirium.

Enrollment: 150 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 65 years
• Classified as American Society of Anesthesiologists I-III
• Hip surgery patients who agreed to the study

Exclusion criteria

• Non-consent to participate
• Diagnosed neurological or psychiatric disorders including schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis
• Coma, dementia, or language impairment affecting communication and assessment
• History of neurosurgery
• Use of antipsychotic medication preoperatively
• Body temperature exceeding 38°C within 24 hours before surgery.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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150 participants in 2 patient groups

Group C

No Intervention group

Description:

Patients in Group C will be covered with a bedsheet intraoperatively without active warming methods employed.

Group W

Experimental group

Description:

Patients in Group W will have a 37°C forced-air warming blanket initiated upon entering the operating room to maintain their body temperature between 36-37 degrees Celsius.

Treatment:

Device: 3M™ Bair Hugger™ Warming Unit