Temporal Pattern of Circulating DNA for Patients Receiving Irradiation

University of Rochester

Status: Terminated

Conditions: Radiation

Study type: Observational

Funder types: Other

Identifiers

NCT01099020

ULAB10008

Details and patient eligibility

About

The purpose of the research study is to test a measurement tool that will determine the radiation dose people receive when they have been accidentally exposed to radiation. This test will be done using a small amount of blood and known dose of radiation.

Enrollment: 13 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient must be scheduled to undergo Total Body Irradiation (TBI) as part of a conditioning regime for a Bone Marrow Transplant. OR, Be scheduled to undergo Radiation Therapy treatment for a malignancy or other disease and have a radiation treatment field that contains at least 2 liters of tissue receiving at least 2 Gy radiation dose over the first 5 days of treatment.
• Patient must be willing to have blood draws as defined below.
• Patient must provide study-specific informed consent prior to study entry.
• Hemoglobin≥8.
• Age ≥ 18, but not older than age 60.

Exclusion criteria

• Patients not meeting the above inclusion criteria.