Testing How Well Magnesium Citrate Capsules Work as Preparation for a Colonoscopy

LifeBridge Health

Status: Completed

Conditions: Colonoscopy

Treatments: Other: Polyethylene Glycol 3350; Other: Dulcolax Tablets; Dietary Supplement: Magnesium Citrate Capsules

Study type: Interventional

Funder types: Other

Identifiers

NCT03247595

1031752

Details and patient eligibility

About

This study compares a colonoscopy preparation composed of magnesium citrate capsules to a preparation of polyethylene glycol solution. The hypothesis is that the magnesium citrate capsules work as well and are better liked by patients due to the lack of taste.

Enrollment: 62 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• • Scheduled for colonoscopy at Sinai Hospital or Woodholme GI Associates

Exclusion criteria

• • Calculated creatinine clearance under 30ml/min

  • On PPI and unable to stop for five days before colonoscopy
  • On H2 blockers and unable to stop for two days before colonoscopy
  • achlorhydria
  • Previous colon surgery
  • Cardiovascular disease, including uncontrolled congestive heart failure, unstable angina pectoris, or recent (3 months) percutaneous transluminal coronary angioplasty, myocardial infarction, or coronary artery bypass graft surgery
  • Colon disease, including chronic constipation (<2 bowel movements per week for >1 year), ileus and/or acute obstruction, ileostomy, right or transverse colostomy, subtotal colectomy (≥50% of colon removed) with ileosigmoidostomy, hypomotility syndrome, megacolon, or idiopathic pseudo-obstruction
  • Pregnant women

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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62 participants in 2 patient groups

Polyethylene Glycol

Active Comparator group

Description:

Polyethylene Glycol 3350: 4 Liters

Treatment:

Other: Polyethylene Glycol 3350

Magnesium Citrate Capsules

Experimental group

Description:

36 Magnesium citrate capsules

Treatment:

Dietary Supplement: Magnesium Citrate Capsules

Other: Dulcolax Tablets