Testing of a Candy in Five Different Versions for the Additional Humidification of the Oral Cavity (DESERTO)

University Hospital Basel

Status: Completed

Conditions: Xerostomia; Dryness of Mouth

Treatments: Other: V01 candy; Other: V02 candy; Other: V04 candy; Other: V05 candy; Other: V03 candy

Study type: Interventional

Funder types: Other

Identifiers

NCT04554342

2020-01942 ex19Filippi3;

Details and patient eligibility

About

This study is to investigate whether a candy can increase moisture of the oral cavity and reduce dryness of mouth.

Full description

A candy (available on the market from a Swiss manufacturer (Ricola)), free of ingredients that could interfere with the investigation, is tested in five different versions on different days. It is to analyse whether these candies can increase moisture of the oral cavity and reduce dryness of mouth.

Enrollment: 33 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• non- smoker
• no allergies
• no drug- use (except for contraception)
• healthy volunteers (no disease/infection 4 weeks before study participation)

Exclusion criteria

• pregnant women

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Triple Blind

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33 participants in 5 patient groups

healthy participants starting with candy V01

Experimental group

Description:

healthy participants testing a candy in 5 different variations by (unstimulated and stimulated) salivary flow rate (before and after comparison)

Treatment:

Other: V05 candy

Other: V03 candy

Other: V02 candy

Other: V04 candy

Other: V01 candy

healthy participants starting with candy V02

Experimental group

Treatment:

Other: V05 candy

Other: V03 candy

Other: V02 candy

Other: V04 candy

Other: V01 candy

healthy participants starting with candy V03

Experimental group

Treatment:

Other: V05 candy

Other: V03 candy

Other: V02 candy

Other: V04 candy

Other: V01 candy

healthy participants starting with candy V04

Experimental group

Treatment:

Other: V05 candy

Other: V03 candy

Other: V02 candy

Other: V04 candy

Other: V01 candy

healthy participants starting with candy V05

Experimental group

Treatment:

Other: V05 candy

Other: V03 candy

Other: V02 candy

Other: V04 candy

Other: V01 candy