Testing Sodium Hypochlorite and Hyaluronic Acid as an Adjunct to Non-Invasive Therapy for Stage III Periodontitis Management

Karim Ismail

Status: Completed

Conditions: Periodontitis; Periodontitis (Stage 3)

Treatments: Other: Scaling and root planing with sodium hypochlorite and hyaluronic acid; Procedure: Scaling and root planing

Study type: Interventional

Funder types: Other

Identifiers

NCT07071467

9208891

Details and patient eligibility

About

The study was designed to evaluate the concept of the clean & seal, using sodium hypochlorite gel and hyaluronic acid as adjunctive to non-surgical therapy for management of Stage III Periodontitis.

Enrollment: 20 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients of both sexes diagnosed with periodontitis Stage III.
• CAL ≥ 5mm or bone loss affecting middle third of the root in more than two adjacent teeth.
• PPD ≥ 6mm in more than two adjacent teeth.
• Periodontal tooth loss ≤ 4 teeth.
• Systemically healthy patients.

Exclusion criteria

• Patient with uncontrolled diabetes.
• Pregnant or lactating.
• Tobacco smoker ≥ 10 cigarettes/day.
• Antibiotic treatment within previous 4 weeks.
• Acute periodontal or periapical abscess

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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20 participants in 2 patient groups

Scaling and root planing with sodium hypochlorite and hyaluronic acid

Experimental group

Treatment:

Other: Scaling and root planing with sodium hypochlorite and hyaluronic acid

Scaling and root planing

Active Comparator group

Treatment:

Procedure: Scaling and root planing