Testing the Efficiency of Karman Curette in the Treatment of Misoprostol Failure in Women With Missed Abortion

Clalit Health Services

Status: Unknown

Conditions: Abortion, Missed

Treatments: Device: Karman curettage

Study type: Interventional

Funder types: Other

Identifiers

NCT02917785

177-16-MMC

Details and patient eligibility

About

the purpose of this study is to examine the success rates of Karman curettage in completing the abortion after failed recurred treatment with Misoprostol for women with missed abortion.

Enrollment: 60 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy women diagnosed with missed abortion treated in Meir Medical Center.
• The abortion occured during the first trimester of pregnancy.
• Patients who chose drug therapy (Misoprostol), after retained products of conception were evident on ultrasound.

Exclusion criteria

• patients with mullarian abnormality (i.e. septal uterus, myoma etc.)
• patients with significant bleeding
• Endometrial wall (residua) greater than 20 mm.
• known or suspected infection
• known clotting defect
• women after cesarean section
• closed cervix

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Karman curettage

Experimental group

Description:

after a retained product of interception is observed in ultrasound examination, the women in this arm will undergo Karman curretage.

Treatment:

Device: Karman curettage

Control

No Intervention group