Testing Two Interventions to Improve Health Outcomes and Quality of Life Among Rural Older Adults Living With HIV

Medical College of Wisconsin

Status: Enrolling

Conditions: HIV

Treatments: Behavioral: Individual Strengths-Based Case Management Intervention; Behavioral: Supportive-Expressive Peer Social Support Group Intervention

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT06269081

R01NR020770 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

Engagement in HIV medical care and adherence to HIV medications are both essential in improving health outcomes among people living with HIV (PLH), but PLH living in rural areas-who suffer higher mortality rates than their urban counterparts-can confront multiple barriers to care engagement and adherence, especially as they face the logistical, medical, and social challenges associated with aging. This project will test the efficacy of two interventions to determine their impact on HIV health outcomes and quality of life among rural, older PLH living in the Southern U.S. The two interventions, adapted from evidence-based interventions and delivered remotely, are: (1) supportive-expressive peer social support groups and (2) strengths-based case management. We hypothesize that both interventions will increase viral suppression, antiretroviral therapy adherence, and health-related quality of life and decrease depressive symptoms. Results from this study will provide us with tools to improve health outcomes for rural older people living with HIV.

Enrollment: 352 estimated patients

Sex: All

Ages: 50+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged 50 years or greater
• Living in a county with a score of .4 or higher on the index of relative rurality (IRR)
• Living in Alabama, Arkansas, Delaware, Florida, Georgia, Kentucky, Louisiana, Maryland, Mississippi, Missouri, North Carolina, Oklahoma, South Carolina, Tennessee, Texas, Virginia, or West Virginia
• Living with HIV
• Has a telephone at home
• Able to provide informed consent

Exclusion criteria

• Not meeting eligibility criteria described above

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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352 participants in 4 patient groups

Supportive-Expressive Peer Social Support Group + Individual Strengths-Based Case Management

Experimental group

Treatment:

Behavioral: Individual Strengths-Based Case Management Intervention

Behavioral: Supportive-Expressive Peer Social Support Group Intervention

Supportive-Expressive Peer Social Support Group

Experimental group

Treatment:

Behavioral: Supportive-Expressive Peer Social Support Group Intervention

Individual Strengths-Based Case Management

Experimental group

Treatment:

Behavioral: Individual Strengths-Based Case Management Intervention

HIV Information Only

No Intervention group

Description:

This arm will not receive either of the interventions but will receive information on successfully aging with HIV.