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This study evaluates the effectiveness and safety of YAG laser peripheral iridotomy performed at two different locations (temporal and inferior) in patients with primary angle-closure glaucoma, a leading cause of blindness worldwide. Patients visiting the glaucoma clinic at Feiz Hospital who are candidates for peripheral iridotomy will participate. In each patient, one eye will receive a temporal iridotomy, and the other eye will receive an inferior iridotomy, with patients unaware of the location used in each eye. The study will measure outcomes such as laser power, intraocular pressure, visual symptoms, and complications over six months to determine which approach is more effective and safer.
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Inclusion and exclusion criteria
Inclusion Criteria:Diagnosis of Primary Angle-Closure Glaucoma.
Adults (typically over 40 years old).
Ability to provide informed consent.
Narrow or closed anterior chamber angle (based on gonioscopy).
Intraocular pressure (IOP) controlled with medication but requiring surgery.
No previous iridotomy.
Exclusion Criteria:econdary glaucoma.
Active eye diseases (e.g., infection or inflammation).
Advanced cataracts or lens-related issues.
Severe visual impairment (e.g., less than 20/200 vision).
Uncontrolled systemic diseases (e.g., diabetes or cardiovascular disease).
Pregnancy or breastfeeding.
Previous eye surgery (except for minor procedures).
Inability to follow-up with scheduled visits.
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Primary purpose
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Interventional model
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150 participants in 1 patient group
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Data sourced from clinicaltrials.gov
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