Testosterone-induced Muscle Memory and Underlying Mechanisms

Morten Hostrup, PhD

Status: Enrolling

Conditions: Skeletal Muscle Physiology

Treatments: Drug: Testosterone Undecanoate

Study type: Interventional

Funder types: Other

Identifiers

NCT06188767

TESTO

Details and patient eligibility

About

The purpose of this project is to investigate underlying mechanisms of testosterone- and resistance training-induced muscle hypertrophy and muscle memory in humans.

Enrollment: 30 estimated patients

Sex: Male

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy men and women
• BMI of <26 and normal ECG and blood pressure

Exclusion criteria

• Smoking
• Chronic disease,
• Use of prescription medication
• Pain due to current or previous musculoskeletal injury
• Resistance training more than once per week in the 12 months leading up to the intervention
• Current or previous use of prohibited anabolic substances

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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30 participants in 2 patient groups, including a placebo group

Testosterone

Experimental group

Description:

Participants are randomized to a single injection of 1000 mg testosterone undecanoate

Treatment:

Drug: Testosterone Undecanoate

Placebo

Placebo Comparator group

Description:

Participants are randomized to a single placebo injection

Treatment:

Drug: Testosterone Undecanoate