Testosterone Replacement Therapy Decreases Plasma Paraoxonase 1 Enzyme Activity In Male Patients With Hypogonadism

Gulhane School of Medicine

Status and phase: Completed; Phase 4

Conditions: Hypogonadism

Treatments: Drug: Sustanon

Study type: Interventional

Funder types: Other

Identifiers

NCT01107067

aa001

Details and patient eligibility

About

The purpose of this study is investigating the effect of testosterone treatment on paraoxonase level in male patients with hypogonadotrophic hypogonadism

Enrollment: 32 patients

Sex: Male

Ages: 20 to 25 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Volunteers patients with hypogonadism

Exclusion criteria

• Coronary heart disease
• Other pituitary/hypothalamic disorders or other non-hypogonadism diseases
• None was receiving vitamins, lipid-lowering drugs, or other medications known to interfere with PON1 activity, lipid profile, or gonadal function

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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32 participants in 1 patient group

testosterone replacement therapy

Experimental group

Treatment:

Drug: Sustanon