Text4Vax: Text Message Reminders for Pediatric COVID-19 and Influenza Vaccines 2024-25 Season

Columbia University

Status: Active, not recruiting

Conditions: COVID-19; Vaccination Hesitancy; Influenza

Treatments: Behavioral: Text message influenza vaccine reminders; Behavioral: Text message influenza and COVID-19 vaccine reminders; Behavioral: Text message COVID-19 vaccine reminders

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT06603090

1R01AI182165 (U.S. NIH Grant/Contract)

AAAV0563-01

Details and patient eligibility

About

This multi-site study assesses the impact of text message reminders on the receipt of COVID-19 and influenza text message reminders takes place primarily in practices from the American Academy of Pediatrics (AAP) Pediatric Research in Office Settings (PROS) network.

Full description

The study is to be conducted over the 1st season (September 2024-April 2025) as an effectiveness trial and the 2nd (September 2025-April 2026) as a replication study. This protocol covers the first season. Parents of eligible children who are 6 month-17 year-old who are due for both a COVID-19 and influenza vaccine will be sent text messages. Within each practice site, parents of eligible children will be randomized to receive either: 1) combined COVID-19 and influenza vaccine text message reminders, 2) COVID-19 reminders alone, 3) influenza reminders alone, or 4) no reminders (usual care).

Randomization is to be stratified by practice site, age group and prior year's COVID-19/influenza vaccine history. Messages will be sent centrally and managed by the research team.

Enrollment: 50,000 estimated patients

Sex: All

Ages: 6 months to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Child that:

  • is 6 months-17 year-old children
  • due for both a COVID-19 and influenza vaccine

• Receives care at study site

• Language listed in electronic health record is English or Spanish

• Has not opted out of text messages from practice

Exclusion criteria

• Has opted out of text messages from practice
• Language listed in electronic health record is not English or Spanish

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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50,000 participants in 4 patient groups

Text message influenza and COVID-19 vaccine reminders

Experimental group

Description:

Text message reminders for both influenza and COVID-19 vaccinations

Treatment:

Behavioral: Text message influenza and COVID-19 vaccine reminders

Text message influenza vaccine reminders

Experimental group

Description:

Text message reminders only for influenza vaccination

Treatment:

Behavioral: Text message influenza vaccine reminders

Text message COVID-19 vaccine reminders

Experimental group

Description:

Text message reminders only for COVID-19 vaccination

Treatment:

Behavioral: Text message COVID-19 vaccine reminders

Usual Care

No Intervention group

Description:

Usual care has no text message