Texture Features and PDL1 in CT-PET 18 FDG

University Hospital Center (CHU)

Status: Completed

Conditions: Non Small Cell Lung Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT04309422

RECHMPL19_0623

Details and patient eligibility

About

Search correlation between texture features in CT-PET 18 FDG and overexpression of PDL1 in non-small cell lung carcinomas during the inital staging.

The hypothesis is that overexpression of PDL1is correlated with at least one texture feature among those selected.

84 CT-PET 18 FDG at the initial staging of a non small cell lung carcinoma (adenocarcinoma or squamous cell carcinoma), whose the biopsed site was the primitive site or the drainage lymphadenopathy, without previous treatment, were recruited and analyzed by a software allowing to estimate texture features.

Enrollment: 84 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria:

• adult patient ;
• first CT-PET 18 FDG realized for the inital staging ;
• absence of previous treatment for a thoracic neoplasm ;
• biopsy realized on the primitive site or local drainage lymphadenopathy ;
• primitive site viewable with morphological imagery ;
• availability of evaluation of PDL1's overexpression ;

Exclusion criteria

• Refusal to participate in this research

Trial design

84 participants in 2 patient groups

Overexpression of PDL1

Description:

Overexpression of PDL1

Absence of overexpression of PDL1

Description:

Absence of overexpression of PDL1