tFUS Imaging & LIFU

Virginia Polytechnic Institute and State University

Status: Withdrawn

Conditions: Brain Imaging

Treatments: Device: Feasibility of imaging using tFUS

Study type: Interventional

Funder types: Other

Identifiers

NCT07222865

25-953

Details and patient eligibility

About

This study is investigating a new method of brain imaging - transcranial functional ultrasound (tFUS). We are comparing the imaging capabilities with functional magnetic resonance imaging (fMRI).

Full description

A battery of tasks will be performed under two imaging conditions. Magnetic Resonance Imaging and transcranial functional ultrasound imaging. Tasks include a breath hold task, an e-stim task, and low-intensity focused ultrasound neuromod.

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• See above.

Exclusion criteria

• Claustrophobia
• Contraindications to MRI (neurostims, metal implants, pacemakers, etc)
• Contraindications to CT (pregnancy)
• Active medical disorders with CNS effects (e.g. Alzheimers)
• History of neurological disorder
• History of head injury with LOC > 10 min
• History of alcohol or drug dependence

Trial design

Primary purpose: Device Feasibility

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

Arm 1 - all participants

Experimental group

Description:

All participants will receive two imaging modalities with corresponding tasks to compare imaging modalities.

Treatment:

Device: Feasibility of imaging using tFUS