Thalassemia Screening by Third Generation Sequencing

Chiang Mai University

Status: Active, not recruiting

Conditions: Thalassemia Trait; Thalassemia; Mixed

Treatments: Procedure: blood draw

Study type: Interventional

Funder types: Other

Identifiers

NCT05552690

513/2021

Details and patient eligibility

About

Test globin gene in participants

Full description

Recruit individuals who documented as thalassemia carrier or disease and who positive thalassemia screening but unknown mutation.

Blood will be sent for third generation sequencing to review alpha and beta globin gene mutation.

Enrollment: 20 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Thalassemia carriers or disease individuals with documented as known globin gene mutation.
2. Thalassemia carriers or disease individuals whose mutation did not retrieve from conventional technique and were assigned as no known mutation

Exclusion criteria

-incomplete medical data

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

20 participants in 1 patient group

Thalassemia screening positive

Other group

Description:

In this study only 1 group of participants. No comparative. Only description

Treatment:

Procedure: blood draw