The Absorption of Vitamin B12 Among Healthy Pregnant Women

University of Aarhus

Status: Completed

Conditions: Pregnancy

Treatments: Dietary Supplement: B12 vitamin (Cyanocobalamin)

Study type: Interventional

Funder types: Other

Identifiers

NCT00730093

BH12008

Details and patient eligibility

About

During pregnancy the woman uses more vitamin B12, but we do not know, whether it is through increased absorption or it eats into the womans vitamin B12 deposit . Sufficient B-vitamin is crucial for the normal development af foetus during pregnancy.

In Denmark the National Board of Health recommend an intake of Folic Acid, from the day the woman wishes to be pregnant and to the 12. week of gestation, but there is no recommendation for vitamin B12. We will measure the vitamin B12 absorption with a new non-radioactive test, CobaSorb.

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Enrollment: 27 patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• the 13 week of gestation +/- 1 week (only fore pregnant women)
• Between 20- 40 years
• Northern European
• abel to read and understand danish

Exclusion criteria

• treatment with vitamin B12 within the last 5 years
• daily intake of vitamins that contain more than 1µg vitamin B12
• infectious disease
• systemic disease
• daily use of medicine that interferes with vitamin B12

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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27 participants in 1 patient group

A

Other group

Treatment:

Dietary Supplement: B12 vitamin (Cyanocobalamin)