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The Acute Effect of Interval-walking (acute IWS)

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Rigshospitalet

Status

Completed

Conditions

Type 2 Diabetes Mellitus

Treatments

Behavioral: Interval Walking
Behavioral: Continuous walking

Study type

Interventional

Funder types

Other

Identifiers

NCT01987258
H-3-2012-141

Details and patient eligibility

About

Four months of interval walking training (IWT) is superior to energy-expenditure matched continuous walking training (CWT) with regards to weight loss and improvements in glycemic control. The reason for this is unclear. One potential explanation for the differential outcome in weight loss is excess post-exercise oxygen consumption (EPOC), which is defined as the elevated oxygen consumption measured during the hours following an exercise bout. A large EPOC means greater energy expenditure which, if energy intake does not change, leads to a greater weight loss. This weight loss may subsequently improve glycemic control

  • Aim 1: To assess the effect of an acute bout of IWT vs. an acute bout of CWT on glycemic control in type 2 diabetics and to assess mechanisms responsible for differences (if any). It is hypothesised that IWT will be more advantageous for improving glycemic control.
  • Aim 2: To examine the effect of an acute bout of IWT vs. an acute bout of CWT on EPOC. It is hypothesised that IWT will produce an EPOC of larger magnitude than CWT.

Enrollment

10 patients

Sex

All

Ages

30 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Diabetes mellitus, type 2

Exclusion criteria

  • Smoking
  • Pregnancy
  • insulin dependence
  • Contraindication to physical activity (as judged by medical history and screening)
  • Evidence of thyroid, liver, lung, kidney or heart disease

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

10 participants in 3 patient groups

Control
No Intervention group
Description:
No exercise (control experiment)
Interval Walking
Experimental group
Description:
A one hour interval walking exercise bout
Treatment:
Behavioral: Interval Walking
Continuous walking
Experimental group
Description:
A one hour continuous walking exercise bout
Treatment:
Behavioral: Continuous walking

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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