The Acute, Synergistic Effects of Protein and Calcium on Appetite and Energy Intake

Northumbria University

Status: Unknown

Conditions: Healthy

Treatments: Dietary Supplement: Calcium; Dietary Supplement: Porridge-based breakfast.; Dietary Supplement: Protein

Study type: Interventional

Funder types: Other

Identifiers

NCT01986036

32AN4

Details and patient eligibility

About

High-protein meals have previously been shown to acutely reduce appetite and energy intake. More recently, meals higher in calcium have also been shown to increase feelings of fullness, circulating insulin and intestinal peptide concentrations and reduce appetite sensations.

This study aims to assess whether calcium and protein act synergistically to acutely influence appetite and energy intake.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male or Female
• BMI 18.5-29.9 kg/m2
• Age: 18-40 years

Exclusion criteria

• Smokers
• Food allergies
• Metabolic disorders (ie. type 2 diabetes)

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

---

20 participants in 4 patient groups

CONTROL

Sham Comparator group

Description:

Control breakfast low in protein and calcium. Porridge-based breakfast.

Treatment:

Dietary Supplement: Porridge-based breakfast.

PROTEIN

Active Comparator group

Description:

High-protein breakfast.

Treatment:

Dietary Supplement: Porridge-based breakfast.

Dietary Supplement: Protein

CALCIUM

Active Comparator group

Description:

High-calcium breakfast.

Treatment:

Dietary Supplement: Calcium

Dietary Supplement: Porridge-based breakfast.

PRO-CAL

Experimental group

Description:

High-protein and calcium breakfast.

Treatment:

Dietary Supplement: Calcium

Dietary Supplement: Porridge-based breakfast.

Dietary Supplement: Protein