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The Addition of Dexmedetomidine on Postoperative Sleep for Middle-aged and Elderly Patients With Gastric Cancer

N

Nanjing PLA General Hospital

Status and phase

Unknown
Phase 3

Conditions

Gastric Cancer

Treatments

Drug: dexmedetomidine

Study type

Interventional

Funder types

Other

Identifiers

NCT03117023
2017NLY002

Details and patient eligibility

About

The purpose of this study is to find out the effect of Dexmedetomidine for treatment of sleep deprivation, pain relief and postoperative recovery on middle-aged and elderly Patients with Gastric Cancer.

Full description

Patients were randomized to receive sufentanil 0.05ug/kh/h + dexmedetomidine 0.1ug/kg/h (DEX group) or sufentanil 0.05ug/kg/h + saline (control group) for 48h. The primary outcome was the total sleep time during the first three days after surgery. The secondary outcomes included pain score, daily sufentanil consumption, time to functional recovery, length of hospital stay and side effects.

Enrollment

50 estimated patients

Sex

All

Ages

55+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Elective gastric cancer operation Age ≧ 55 years ASA classification:I to III, BMI: 18-30 kg/m2 without the history of gastrointestinal surgery the normal coagulation function -

Exclusion criteria

the history of gastrointestinal surgery Gastrostomy and jejunostomy sleep apnea syndrome or severe osahs Severe liver and heart dysfunction Severe mental illness

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Quadruple Blind

50 participants in 2 patient groups

dexmedetomidine group
Experimental group
Description:
sufentanil + dexmedetomidine
Treatment:
Drug: dexmedetomidine
control group
No Intervention group
Description:
sufentanil + saline

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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