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The Addition of Hydromorphone to Local Anesthetics for the Repair of Inguinal Hernias in Elderly Patients

J

Jilin University

Status

Completed

Conditions

Inguinal Hernia

Treatments

Drug: Hydromorphone combined with ropivacaine
Drug: Ropivacaine

Study type

Interventional

Funder types

Other

Identifiers

NCT06218160
2022/148

Details and patient eligibility

About

To compare the clinical and postoperative analgesic effects of hydromorphone combined with ropivacaine and ropivacaine alone in quadrangular muscle block for open inguinal hernia in elderly patients.

Full description

Elderly patients selected for Lichtenstein hernia repair in our hospital who met the inclusion and exclusion criteria and obtained informed consent were included in this trial, and were randomly divided into experimental group by random number table method: 0.375% ropivacaine combined with hydromorphone block group, and control group: 0.375% ropivacaine block group alone.

Enrollment

63 patients

Sex

All

Ages

60+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age 60 and above.
  • Admission to hospital for open inguinal hernia surgery is consistent with the -indications of this surgical modality, ASA grades 1 to 3.
  • No recent use of sedatives, opioids, or other analgesics.
  • Good compliance, signed informed consent.
  • Complete clinical data.

Exclusion criteria

  • There are serious cardiovascular and cerebrovascular diseases.
  • Abdominal infection.
  • Coagulation dysfunction or receiving anticoagulation therapy.
  • Local anesthesia drug allergy.
  • Can not cooperate with the corresponding operation, suffering from mental illness.
  • Previous surgical history of the corresponding position in the abdomen that may interfere with the surgical process of this study.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

63 participants in 2 patient groups

Hydromorphone combined with ropivacaine
Experimental group
Description:
The posterior quadrat block was performed by adding 1mg hydromorphone to 0.375% ropivacaine in a total of 30ml.
Treatment:
Drug: Hydromorphone combined with ropivacaine
ropivacaine
Active Comparator group
Description:
A mixture of 0.375% ropivacaine for a total of 30ml was performed for posterior quadrate block.
Treatment:
Drug: Ropivacaine

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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